Caution - increased level of tramadol due to 2D6 inhibition. Titrate with extreme caution due to risk of overdose. If already established on tramadol, may require dose reduction. Consider choosing an alternative agent.
No clinically significant drug interactions identified.
No clinically significant drug interactions identified.
No clinically significant drug interactions identified.
No clinically significant drug interactions identified.
Caution - increased level of warfarin due to 1A2/3A4/2C9/2C19 inhibition. Monitor INR more closely after initiation of abiraterone therapy or dose changes. Titrate warfarin dose to target INR.
No clinically significant drug interactions identified.