Drug Interactions

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Abiraterone Interactions

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Tramadol-acetaminophen

Caution - increased level of tramadol due to 2D6 inhibition. Titrate with extreme caution due to risk of overdose. If already established on tramadol, may require dose reduction. Consider choosing an alternative agent.

Trazodone

No clinically significant drug interactions identified.

Valsartan

No clinically significant drug interactions identified.

Venlafaxine

No clinically significant drug interactions identified.

Verapamil

No clinically significant drug interactions identified.

Warfarin

Caution - increased level of warfarin due to 1A2/3A4/2C9/2C19 inhibition. Monitor INR more closely after initiation of abiraterone therapy or dose changes. Titrate warfarin dose to target INR.

Zopiclone

No clinically significant drug interactions identified.

Selected Drugs

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