A Multicentre Retrospective Analysis of Toxicity in 6-weekly Versus 3-weekly Pembrolizumab

Journal of Immunotherapy. 2021; 00: 000-000

A real-world study on the safety of the extended dosing schedule for nivolumab and pembrolizumab in patients with solid tumors

International Immunopharmacology. 2022; 108: 108775. doi: 10.1016/j.intimp.2022.108775

A real-world study on the safety profile of extended-interval dosing of immune checkpoint inhibitors for melanoma: a single-center analysis in Japan

Frontiers in Medicine. 2023; 10: 1293397. doi: 10.3389/fmed.2023.1293397

A six-weekly dosing schedule for pembrolizumab in patients with cancer based on evaluation using modeling and simulation

European Journal of Cancer. 2020; 131; 68-75

Adoption of Extended-Interval Dosing of Single-Agent Pembrolizumab and Comparative Effectiveness vs Standard Dosing in Time-to-Treatment Discontinuation

JAMA Oncol. 2022; 8(11): 1663-1667

Alternate Pembrolizumab Dosing Interval in Advanced NSCLC with PD-L1 TPS ≥ 50%: 3 Weekly Compared to 6 Weekly Dosing

Current Oncology. 2022; 29(11): 8686-8692

Association of Extended Dosing Intervals or Delays in Pembrolizumab-based Regimens with Survival Outcomes in Advanced Non-small cell Lung Cancer

Clinical Lung Cancer. 2021; 22(3): e379-389

Comparison of clinical safety between standard versus extended interval dosing of immune checkpoint inhibitors: a real-world retrospective cohort study

ESMO Open 2023; 8(6):102070. doi: 10.1016/j.esmoop.2023.102070

Dosage of anti-PD-1 monoclonal antibodies: a cardinal open question

Clinical and translational oncology. 2021; 23(8): 1511-1519

Extended interval dosing in patients with cancer receiving immune checkpoint inhibitors: Safety analysis from the EDICI study

Journal of Clinical Oncology. 2022 ASCO Annual Meeting. Abstract 2595

Extended-Interval Dosing Strategy of Immune Checkpoint Inhibitors in Lung Cancer: Will it Outlast the COVID-19 Pandemic?

Frontiers of Oncology. 2020; 10(1193): 1-9

Extending the dosing intervals of nivolumab: model-based simulations in unselected cancer patients

2024; 130(11): 1866-1874

High response rate with extended dosing of cemiplimab in advanced cutaneous squamous cell carcinoma

Journal for Immunotherapy of Cancer. 2024; 12(3): e008325.doi: 10.1136/jitc-2023-008325

Immune-checkpoint inhibitors for lung cancer patients amid the COVID-19 pandemic: a case report of severe meningoencephalitis after switching to an extended-interval higher flat-dose nivolumab regimen

2021; 10(4): 1917-1923

Impact of extended interval dosing of immune checkpoint inhibitors in lung cancer patients during the COVID-19 pandemic

2023; 83:101004. doi: 10.1016/j.resmer.2023.101004

KEYNOTE-555 Cohort B: Efficacy, safety, and PK of pembrolizumab 400 mg every 6 weeks (Q6W) as 1L therapy for advanced melanoma

Journal of Clinical Oncology. 2021 ASCO Annual Meeting. Abstract 9541

Model-informed drug development approach supporting approval of the 4-week (Q4W) dosing schedule for nivolumab (Opdivo) across multiple indications: a regulatory perspective

Annals of Oncology. 2019; 30(4): 644-651

Multinational Analysis of Estimated Health Care Costs Related to Extended-Interval Fixed Dosing of Checkpoint Inhibitors

JAMA Network Open. 2023; 6(2): e230490. doi:10.1001/jamanetworkopen.2023.0490

Safety and Efficacy of Extended Interval Dosing for Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer During the COVID-19 Pandemic

2022; 23(2): 143-150

Safety of Extended-Interval Dosing Strategy of Immune Checkpoint Inhibitors for Advanced NSCLC

Journal of Thoracic Oncology. 2023; 18(2): e14-e16

Safety of extended interval dosing immune checkpoint inhibitors: a multicenter cohort study

Journal of National Cancer Institute. 2023; 00(0): 1-9

Utilization of pharmacokinetics in the dosing of pembrolizumab in non-small cell lung cancer

AME Clinical Trials Review. 2024; 2: 17

When Less May Be Enough: Dose Selection Strategies for Immune Checkpoint Inhibitors Focusing on AntiPD-(L)1 Agents

Targeted Oncology. 2022; 17(3): 253-270