Imjudo®
CTLA-4 Inhibitor
300 mg IV x 1 dose OR 4 mg/kg IV x 1 dose for low weight patients (<30 kg)
Not applicable due to dosing schedule.
300mg
Not applicable (only given x 1 dose)
Durvalumab (1L BCLC Stage C Hepatocellular Carcinoma) - 300 mg IV x 1 dose prior to durvalumab.
Administered IV over 60 minutes.
25 mg and 300 mg (20 mg/mL)
Flat dose-response and dose-toxicity relationship, unlike ipilimumab which displays a dose dependent efficacy and toxicity profile.
17-18 days (85-90 days)